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CD147 Mouse anti-Human, Alexa Fluor 647, Clone: HIM6, BD

Product Code. 15822029
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Product Code. 15822029 Supplier BD Biosciences Supplier No. 562551

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Description

Mouse Monoclonal Antibody

The HIM6 monoclonal antibody specifically binds to CD147 which is encoded by BSG. CD147 is a type I transmembrane glycoprotein (30-50 kDa) of the immunoglobulin super-gene family. Neurothelin, a blood-brain barrier-specific molecule, was clustered as CD147 in the Sixth Human Leukocyte Differentiation Antigen (HLDA) workshop. It bears homology with mouse gp42 or basigin, human “M6” or “EMMPRIN”, rat OX-47 or CD-9, and avian HT7 or 5A11. CD147 is also known as Tumor cell-derived collagenase stimulatory factor (TCSF). CD147 is a molecule that is broadly expressed on cells of hematopoietic and non-hematopoietic origin. Its expression on specific cell types may be regulated by cytokines. CD147 plays a role in embryonal blood-brain barrier development and a role in integrin-mediated adhesion in brain endothelia.

TRUSTED_SUSTAINABILITY

Specifications

Antigen CD147
Applications Flow Cytometry
Classification Monoclonal
Clone HIM6
Conjugate Alexa Fluor 647
Description BSG; Basigin; BASI; Neurothelin; 5F7; EMMPRIN; M6; OK; TCSF
Formulation Aqueous buffered solution containing BSA and ≤0.09% sodium azide.
Host Species Mouse
Purification Method Affinity Purified
Quantity 50 Tests
Regulatory Status RUO
Primary or Secondary Primary
Target Species Human
Content And Storage Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Isotype IgG1 κ
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