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Description
Reacts with CD25, a 55kDa glycoprotein known as the low-affinity interleukin-2 receptor (IL-2R). CD25 is expressed on activated lymphocytes (T and B) and monocytes, and associates with the p75 high-affinity receptor chain to form the IL-2R complex. The CD25 molecule reveals three epitope regions: A, B, and C. M-A251 antibody recognizes epitope region B. CD25 expression on lymphocytes is upregulated by anti-CD3 or PHA stimulation. Soluble IL-2R is produced following inflammatory responses.
Specifications
| CD25 | |
| Monoclonal | |
| APC-H7 | |
| Aqueous buffered solution containing BSA, protein stabilizer, and ≤0.09% sodium azide. | |
| Affinity Purified | |
| RUO | |
| Primary | |
| Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze. |
| Flow Cytometry | |
| M-A251 | |
| IL-2R; IL2RA; IL-2Rα; TCGFR; TAC antigen; p55 | |
| Mouse | |
| 100 Tests | |
| Immunology | |
| Baboon, Cynomolgus, Human, Rhesus Monkey | |
| IgG1 κ |
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