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CD294 Rat anti-Human, PerCP-Cy5.5, Clone: BM16, BD

Product Code. 15871209
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50 μg
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Product Code. 15871209 Supplier BD Biosciences Supplier No. 561660

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Description

Rat Monoclonal Antibody

The BM16 monoclonal antibody specifically binds to CRTH2 (chemoattractant receptor-homologous molecule expressed on Th2 cells). CRTH2 is a member of the G protein-coupled leukocyte chemoattractant receptor family and it is expressed on Th2, but not Th1 lineage cells. It is detectable on CD4+ T cells in fresh PBMC and no significant expression on B cells and NK cells. CRTH2 is also expressed on peripheral blood basophils and eosinophils, suggesting its involvement allergic reactions. Phenotypic analysis of CD4+ T cells expressing CRTH2 demonstrated CD45RA-, CD45RO+ and CD25+. These cells produce Th2- but little or no Th1-type cytokines upon stimulation with PMA and Ionomycin.

TRUSTED_SUSTAINABILITY

Specifications

Antigen CD294
Applications Flow Cytometry
Classification Monoclonal
Clone BM16
Concentration 0.2mg/mL
Conjugate PerCP-Cyanine5.5
Description CRTH2; PTGDR2 ; Prostaglandin D2 receptor 2; DL1R; DP2; GPR44
Formulation Aqueous buffered solution containing ≤0.09% sodium azide.
Host Species Rat
Immunogen Human CRTH2 Transfected Cell Line
Purification Method Affinity Purified
Quantity 50 μg
Regulatory Status RUO
Primary or Secondary Primary
Target Species Human
Content And Storage Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Isotype IgG2a κ
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