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CD31 (PECAM-1) Mouse anti-Human, Biotin, Clone: WM-59 (WM59), eBioscience™

Mouse Monoclonal Antibody

Merk:  Affymetrix eBioscience 13-0319-82

Overige gegevens : Gewicht : 0.25000kg

 Bekijk meerdere types van dit product via de

Produktcode. 15249529

  • € 162.00 / 100 µg


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Beschrijving

Beschrijving

CD31 (platelet endothelial cell adhesion molecule-1, PECAM-1) is an inhibitory coreceptor involved in regulation of T cell and B cell signaling by a dual immunoreceptor tyrosine-based inhibitory motif (ITIM) that upon associated kinases-mediated phosphorylation provide docking sites for protein-tyrosine phosphatases. CD31 is expressed ubiquitously within the vascular compartment and is located mainly at junctions between adjacent cells. N-terminal Ig-like domain of CD31 is responsible for its homophilic binding, which plays an important role in cell-cell interactions. CD31 is a multifunctional molecule with diverse roles in modulation of integrin-mediated cell adhesion, transendothelial migration, angiogenesis, apoptosis, negative regulation of immunoreceptor signaling, autoimmunity, macrophage phagocytosis, IgE-mediated anaphylaxis and thrombosis. It is one of key regulatory molecules in vascular system.
Specificatie

Specificatie

CD31 (PECAM-1)
Monoclonal
0.5 mg/mL
PBS with 0.1% gelatin and 0.09% sodium azide; pH 7.2
P16284
CD31 antigen, CD31/EndoCAM, GPIIA′, PECA1, PECAM-1, CD31/EndoCAM, adhesion molecule, endoCAM, platelet endothelial cell adhesion molecule
Mouse
Affinity chromatography
RUO
Antibody
Monoclonal
Human
Flow Cytometry
WM-59 (WM59)
Biotin
PECAM1
Liquid
PECAM1
IgG1, kappa
100 μg
4° C, store in dark, DO NOT FREEZE!
Primary
5175
Video's
Documentatie

For Research Use Only.