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CD49b Mouse anti-Human, FITC, Clone: AK-7, BD

Product Code. 15868218
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100 Tests
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Product Code. 15868218 Supplier BD Biosciences Supplier No. 555498

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Mouse Monoclonal Antibody

The AK-7 monoclonal antibody specifically binds to CD49b. CD49b is also known as integrin α2 chain, VLA-α2, and GP1a. CD49b is a type I transmembrane glycoprotein and be longs to the integrin family of extracellular matrix and cell-cell adhesion receptors. CD49b is expressed on numerous cell types including platelets, activated T cells, B cells, and monocytes. CD49b noncovalently associates with CD29 to form the VLA-2 complex (integrin α 2/ β 1). The VLA-2 complex serves as a receptor for collagen and laminin. It can regulate responses mediated by proinflammatory effector cells.

TRUSTED_SUSTAINABILITY

Specifications

Antigen CD49b
Applications Flow Cytometry
Classification Monoclonal
Clone AK-7
Conjugate FITC
Description Integrin α2 chain; VLA-α2: GP1a
Formulation Aqueous buffered solution containing BSA and ≤0.09% sodium azide.
Host Species Mouse
Purification Method Affinity Purified
Quantity 100 Tests
Regulatory Status RUO
Research Discipline Immunology
Primary or Secondary Primary
Target Species Human
Content And Storage Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Isotype IgG1 κ
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For Research Use Only.

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