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Description
The RIKO-5 antibody reacts with the membrane-associated complement regulator CD55, also known as decayaccelerating factor (DAF).CD55 is expressed on the surface of erythrocytes and most splenic leukocytes, including B and T lymphocytes and CD11b-positive splenocytes,but it is not detected on thymocytes.Immunohistochemical staining (using a different monoclonal antibody) demonstrates that CD55 is expressed on vascular endothelium and many other cells types in a wide variety of organs.In the mouse, there are two isoforms of CD55, transmembrane and GPI-anchored, that are recognized by the RIKO-5 antibody.Both isoforms are able to protect cells from complement attack by inhibiting the deposition of C3 on antibody-sensitized cells,but the RIKO-5 antibody is not able to neutralize this activity. CD97, a member of the EGF-TM7 family that is widely expressed in mouse tissues, is another ligand for CD55.
Specifications
| CD55 | |
| Monoclonal | |
| 0.2mg/mL | |
| DAF, decay-accelerating factor | |
| Hamster | |
| 0.1 mg | |
| Primary | |
| Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze. |
| Flow Cytometry | |
| RIKO-5 | |
| PE | |
| Aqueous buffered solution containing ≤0.09% sodium azide. | |
| Affinity Purified | |
| RUO | |
| Mouse | |
| IgG3 λ |
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Product Title
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