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dynactin 2 (p50), Rabbit, Purified MaxPab™ Polyclonal Antibody, Abnova™
Description
This gene encodes a 50kDa subunit of dynactin, a macromolecular complex consisting of 10-11 subunits ranging in size from 22 to 150kDa. Dynactin binds to both microtubules and cytoplasmic dynein. It is involved in a diverse array of cellular functions, including ER-to-Golgi transport, the centripetal movement of lysosomes and endosomes, spindle formation, chromosome movement, nuclear positioning, and axonogenesis. This subunit is present in 4-5 copies per dynactin molecule. It contains three short alpha-helical coiled-coil domains that may mediate association with self or other dynactin subunits. It may interact directly with the largest subunit (p150) of dynactin and may affix p150 in place. [provided by RefSeq
Specifications
Specifications
| Antigen | dynactin 2 (p50) |
| Applications | Western Blot |
| Classification | Polyclonal |
| Conjugate | Unconjugated |
| Description | Rabbit polyclonal antibody raised against a full-length human DCTN2 protein. |
| Formulation | PBS with no preservative; pH 7.4 |
| Gene | DCTN2 |
| Gene Accession No. | BC000718 |
| Gene Alias | DCTN50/DYNAMITIN/RBP50 |
| Gene Symbols | DCTN2 |
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