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dynactin 2 (p50), Rabbit, Purified MaxPab™ Polyclonal Antibody, Abnova™

Product Code. 16147118
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100 μg
Unit Size:
100µg
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16147118 100 μg 100µg
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Product Code. 16147118 Supplier Abnova Supplier No. H00010540D01P.100ug

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Rabbit polyclonal antibody raised against a full-length human DCTN2 protein.

This gene encodes a 50kDa subunit of dynactin, a macromolecular complex consisting of 10-11 subunits ranging in size from 22 to 150kDa. Dynactin binds to both microtubules and cytoplasmic dynein. It is involved in a diverse array of cellular functions, including ER-to-Golgi transport, the centripetal movement of lysosomes and endosomes, spindle formation, chromosome movement, nuclear positioning, and axonogenesis. This subunit is present in 4-5 copies per dynactin molecule. It contains three short alpha-helical coiled-coil domains that may mediate association with self or other dynactin subunits. It may interact directly with the largest subunit (p150) of dynactin and may affix p150 in place. [provided by RefSeq

Sequence: MADPKYADLPGIARNEPDVYETSDLPEDDQAEFDAEELTSTSVEHIIVNPNAAYDKFKDKRVGTKGLDFSDRIGKTKRTGYESGEYEMLGEGLGVKETPQQKYQRLLHEVQELTTEVEKIKTTVKESATEEKLTPVLLAKQLAALKQQLVASHLEKLLGPDAAINLTDPDGALAKRLLLQLEATKNSKGGSGGKTTGTPPDSSLVTYELHSRPEQDKFSQAAKVAELEKRLTELETAVRCDQDAQNPLSAGLQGACLMETVELLQAKVSALDLAVLDQVEARLQSVLGKVNEIAKHKASVEDADTQSKVHQLYETIQRWSPIASTLPELVQRLVTIKQLHEQAMQFGQLLTHLDTTQQMIANSLKDNTTLLTQVQTTMRENLATVEGNFASIDERMKKLGK

Specifications

Antigen dynactin 2 (p50)
Applications Western Blot
Classification Polyclonal
Conjugate Unconjugated
Description Rabbit polyclonal antibody raised against a full-length human DCTN2 protein.
Formulation PBS with no preservative; pH 7.4
Gene DCTN2
Gene Accession No. BC000718
Gene Alias DCTN50/DYNAMITIN/RBP50
Gene Symbols DCTN2
Host Species Rabbit
Immunogen DCTN2 (AAH00718.1, 1 a.a. ∼ 401 a.a) full-length human protein.
Purification Method Affinity Purified
Quantity 100 μg
Regulatory Status RUO
Research Discipline Cell Cycle
Primary or Secondary Primary
Gene ID (Entrez) 10540
Target Species Human
Content And Storage Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
Product Type Antibody
Isotype IgG
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