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Invitrogen™ Dynactin 2 Polyclonal Antibody
Rabbit Polyclonal Antibody
Brand: Invitrogen™ PA530389
This item is not returnable.
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Description
Recommended positive controls: MCF-7. Predicted reactivity: Mouse (95%), Rat (96%), Xenopus laevis (80%), Chimpanzee (99%), Bovine (98%). Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
This gene encodes a 50-kD subunit of dynactin, a macromolecular complex consisting of 10-11 subunits ranging in size from 22 to 150 kDa. Dynactin binds to both microtubules and cytoplasmic dynein. It is involved in a diverse array of cellular functions, including ER-to-Golgi transport, the centripetal movement of lysosomes and endosomes, spindle formation, chromosome movement, nuclear positioning, and axonogenesis. This subunit is present in 4-5 copies per dynactin molecule. It contains three short alpha-helical coiled-coil domains that may mediate association with self or other dynactin subunits. It may interact directly with the largest subunit (p150) of dynactin and may affix p150 in place.
Specifications
| Dynactin 2 | |
| Polyclonal | |
| Unconjugated | |
| DCTN2 | |
| 2310042E05Rik; 50 kDa dynein-associated polypeptide; C130077D06Rik; C87049; DCTN2; dctn2 protein; DCTN50; DCTN-50; dynactin 2; dynactin 2 (p50); dynactin complex 50 kDa subunit; Dynactin subunit 2; dynamitin; epididymis secretory protein Li 77; GMP23-48K; Growth cone membrane protein 23-48K; HEL-S-77; hypothetical protein LOC527201; p50; p50 dynamitin; p50/dynamitin; RBP50; zgc:63867 | |
| Rabbit | |
| Antigen affinity chromatography | |
| RUO | |
| 10540 | |
| Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. | |
| Liquid |
| Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry | |
| 1 mg/mL | |
| PBS with 1% BSA, 20% glycerol and 0.01% thimerosal; pH 7 | |
| Q13561 | |
| DCTN2 | |
| Recombinant protein encompassing a sequence within the center region of human DCTN2. The exact sequence is proprietary. | |
| 100 μL | |
| Primary | |
| Human | |
| Antibody | |
| IgG |
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