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EGF Receptor Mouse, Unlabeled, Clone: 13, BD
Description
Epidermal Growth Factor (EGF) elicits a variety of cellular responses that are initiated by EGF receptor (EGF-R) binding and activation of intrinsic tyrosine kinase activity. Following ligand binding, EGF receptor is autophosphorylated and, in turn, phosphorylates several other endogenous proteins including phospholipase C γ . These events initiate a number of intracellular responses that include increased levels of intracellular Ca2+ and transient expression of the nuclear oncogene products c-Myc and c-Fos.
Specifications
Specifications
| Antigen | EGF Receptor |
| Applications | Western Blot |
| Classification | Monoclonal |
| Clone | 13 |
| Concentration | 250μg/mL |
| Conjugate | Unconjugated |
| Formulation | Aqueous buffered solution containing BSA, glycerol, and ≤0.09% sodium azide. |
| Host Species | Mouse |
| Immunogen | Human EGF Receptor aa. 1020 to 1046 |
| Purification Method | Affinity Purified |
| Show More |
For Research Use Only.
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