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GNAQ, Mouse, Clone: 3B9, Abnova™
Description
Guanine nucleotide-binding proteins are a family of heterotrimeric proteins that couple cell surface, 7-transmembrane domain receptors to intracellular signaling pathways. Receptor activation catalyzes the exchange of GTP for GDP bound to the inactive G protein alpha subunit resulting in a conformational change and dissociation of the complex. The G protein alpha and beta-gamma subunits are capable of regulating various cellular effectors. Activation is terminated by a GTPase intrinsic to the G-alpha subunit. G-alpha-q is the alpha subunit of one of the heterotrimeric GTP-binding proteins that mediates stimulation of phospholipase C-beta (MIM 600230).[supplied by OMIM
Specifications
Specifications
| Antigen | GNAQ |
| Applications | ELISA, Western Blot |
| Classification | Monoclonal |
| Clone | 3B9 |
| Conjugate | Unconjugated |
| Description | Mouse monoclonal antibody raised against a partial recombinant GNAQ. |
| Formulation | PBS with no preservative; pH 7.4 |
| Gene | GNAQ |
| Gene Accession No. | NM_002072 |
| Gene Alias | G-ALPHA-q/GAQ |
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