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GP1BA, Mouse, Clone: 2E5, Abnova™

Mouse monoclonal antibody raised against a partial recombinant GP1BA.

Brand:  Abnova H00002811-M03.100ug

Product Code. 16148824

  • € 349.00 / 100µg

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This item is not returnable. View return policy

Description

Description

Glycoprotein Ib (GP Ib) is a platelet surface membrane glycoprotein composed of a heterodimer, an alpha chain and a beta chain, that are linked by disulfide bonds. The Gp Ib functions as a receptor for von Willebrand factor (VWF). The complete receptor complex includes noncovalent association of the alpha and beta subunits with platelet glycoprotein IX and platelet glycoprotein V. The binding of the GP Ib-IX-V complex to VWF facilitates initial platelet adhesion to vascular subendothelium after vascular injury, and also initiates signaling events within the platelet that lead to enhanced platelet activation, thrombosis, and hemostasis. This gene encodes the alpha subunit. Several polymorphisms and mutations have been described in this gene, some of which are the cause of Bernard-Soulier syndromes and platelet-type von Willebrand disease. [provided by RefSeq

Sequence: ICEVSKVASHLEVNCDKRNLTALPPDLPKDTTILHLSENLLYTFSLATLMPYTRLTQLNLDRCELTKLQVDGTLPVLGTLDLSHNQLQSLPLLGQTLPALTVLDVPFNRL
Specifications

Specifications

GP1BA
Monoclonal
Unconjugated
PBS with no preservative; pH 7.4
BC027955
GP1BA
GP1BA (AAH27955, 19 a.a. ∼ 128 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
100 μg
Primary
Human
Antibody
IgG2a κ
ELISA
2E5
Mouse monoclonal antibody raised against a partial recombinant GP1BA.
GP1BA
BSS/CD42B/CD42b-alpha/GP1B/MGC34595
Mouse
Affinity chromatography
RUO
2811
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
Liquid
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