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hepcidin antimicrobial peptide, Mouse, Clone: 1F9, Abnova™
Mouse monoclonal antibody raised against a full-length recombinant HAMP.
Brand: Abnova H00057817-M02.100ug
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Description
The product encoded by this gene is involved in the maintenance of iron homeostasis, and it is necessary for the regulation of iron storage in macrophages, and for intestinal iron absorption. The preproprotein is post-translationally cleaved into mature peptides of 20, 22 and 25 amino acids, and these active peptides are rich in cysteines, which form intramolecular bonds that stabilize their beta-sheet structures. These peptides exhibit antimicrobial activity. Mutations in this gene cause hemochromatosis type 2B, also known as juvenile hemochromatosis, a disease caused by severe iron overload that results in cardiomyopathy, cirrhosis, and endocrine failure. [provided by RefSeq
Sequence: SVFPQQTGQLAELQPQDRAGARASWMPMFQRRRRRDTHFPICIFCCGCCHRSKCGMCCKTSpecifications
| hepcidin antimicrobial peptide | |
| Monoclonal | |
| Unconjugated | |
| PBS with no preservative; pH 7.4 | |
| BC020612 | |
| HAMP | |
| HAMP (AAH20612, 25 a.a. ∼ 84 a.a) full-length recombinant protein with GST tag. MW of the GST tag alone is 26 KDa. | |
| 100 μg | |
| Yes | |
| 57817 | |
| Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing. | |
| IgG1 κ |
| ELISA, Western Blot | |
| 1F9 | |
| Mouse monoclonal antibody raised against a full length recombinant HAMP. | |
| HAMP | |
| HEPC/HEPCIDIN/HFE2B/LEAP-1/LEAP1/PLTR | |
| Mouse | |
| Affinity Purified | |
| RUO | |
| Primary | |
| Human | |
| Antibody |
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