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HLA-DQ Mouse anti-Human, FITC, Clone: SK10, BD

Product Code. 15836098
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Product Code. 15836098 Supplier BD Biosciences Supplier No. 347453

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Description

Mouse Monoclonal Antibody

The Anti–HLA-DQ antibody, clone SK10, is derived from the hybridization of NS-1 mouse myeloma cells with spleen cells isolated from BALB/c mice immunized with tonsillar B lymphocytes (non–E-rosetting cells).

Anti-HLA-DQ (Leu-10) recognizes a class II major histocompatibility complex (MHC) antigen, Mr 26 to 34 kdaltons (kDa), distinct from HLA-DR and HLA-DP antigens. Anti-HLA-DQ recognizes a common polymorphic epitope present on HLA-DQ molecules of cells expressing DQw1 and DQw3 (usually associated with DR1, DR2, DR4, DR5, DRw8, DRw9, and DRw10) and absent from DQw2 (usually associated with DR3, and DR7). Therefore, Anti-HLA-DQ will not react with cells from DR3 or DR 7 homozygotes or DR3/7 heterozygotes.

TRUSTED_SUSTAINABILITY

Specifications

Antigen HLA-DQ
Applications Flow Cytometry
Classification Monoclonal
Clone SK10
Concentration 25μg/mL
Conjugate FITC
Formulation Phosphate buffered saline with gelatin and 0.1% sodium azide.
Host Species Mouse
Quantity 100 Tests
Regulatory Status RUO
Research Discipline Immunology
Primary or Secondary Primary
Target Species Human
Content And Storage Store vials at 2-8°C. Conjugated forms should not be frozen and should be protected from prolonged exposure to light. Each reagent is stable for the period shown on the bottle label when stored as directed.
Isotype IgG1 κ
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For Research Use Only.

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