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v-Ha-ras Harvey rat sarcoma viral oncogene homolog, Mouse, Polyclonal Antibody, Abnova™

Mouse polyclonal antibody raised against a full-length human HRAS protein.

Brand:  Abnova H00003265-B01.50uL

Product Code. 16189594

  • € 349.00 / 50µL

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Description

Description

This gene belongs to the Ras oncogene family, whose members are related to the transforming genes of mammalian sarcoma retroviruses. The products encoded by these genes function in signal transduction pathways. These proteins can bind GTP and GDP, and they have intrinsic GTPase activity. This protein undergoes a continuous cycle of de- and re-palmitoylation, which regulates its rapid exchange between the plasma membrane and the Golgi apparatus. Mutations in this gene cause Costello syndrome, a disease characterized by increased growth at the prenatal stage, growth deficiency at the postnatal stage, predisposition to tumor formation, mental retardation, skin and musculoskeletal abnormalities, distinctive facial appearance and cardiovascular abnormalities. Defects in this gene are implicated in a variety of cancers, including bladder cancer, follicular thyroid cancer, and oral squamous cell carcinoma. Multiple transcript variants, which encode different isoforms, have been identified for this gene. [provided by RefSeq

Sequence: MTEYKLVVVGAGGVGKSALTIQLIQNHFVDEYDPTIEDSYRKQVVIDGETCLLDILDTAGQEEYSAMRDQYMRTGEGFLCVFAINNTKSFEDIHQYREQIKRVKDSDDVPMVLVGNKCDLAARTVESRQAQDLARSYGIPYIETSAKTRQGVEDAFYTLVREIRQHKLRKLNPPDESGPGCMSCKCVLS
Specifications

Specifications

v-Ha-ras Harvey rat sarcoma viral oncogene homolog
Polyclonal
Mouse polyclonal antibody raised against a full-length human HRAS protein.
HRAS
C-BAS/HAS/C-H-RAS/C-HA-RAS1/CTLO/H-RASIDX/HAMSV/HRAS1/K-RAS/N-RAS/RASH1
Mouse
50 μL
Cell Cycle
Primary
Human
Serum
Western Blot
Unconjugated
No additive
NM_005343
HRAS
HRAS (NP_005334, 1 a.a. ∼ 189 a.a) full-length human protein.
RUO
Yes
3265
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
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