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heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa), Mouse, Polyclonal Antibody, Abnova™
Mouse polyclonal antibody raised against a full-length recombinant HSPA5.
Brand: Abnova H00003309-A01.50uL
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Description
When Chinese hamster K12 cells are starved of glucose, the synthesis of several proteins, called glucose-regulated proteins (GRPs), is markedly increased. Hendershot et al. (1994) [PubMed 8020977] pointed out that one of these, GRP78 (HSPA5), also referred to as 'immunoglobulin heavy chain-binding protein' (BiP), is a member of the heat-shock protein-70 (HSP70) family and is involved in the folding and assembly of proteins in the endoplasmic reticulum (ER). Because so many ER proteins interact transiently with GRP78, it may play a key role in monitoring protein transport through the cell.[supplied by OMIM
Sequence: EEEDKKEDVGTVVGIDLGTTYSCVGVFKNGRVEIIANDQGNRITPSYVAFTPEGERLIGDAAKNQLTSNPENTVFDAKRLIGRTWNDPSVQQDIKFLPFKVVEKKTKPYIQVDIGGGQTKTFAPEEISAMVLTKMKETAEAYLGKKVTHAVVTVPAYFNDAQRQATKDAGTIAGLNVMRIINEPTAAAIAYGLDKREGEKNILVFDLGGGTFDVSLLTIDNGVFEVVATNGDTHLGGEDFDQRVMEHFIKLYKKKTGKDVRKDNRAVQKLRREVEKAKRALSSQHQARIEIESFYEGEDFSETLTRAKFEELNMDLFRSTMKPVQKVLEDSDLKKSDIDEIVLVGGSTRIPKIQQLVKEFFNGKEPSRGINPDEAVAYGAAVQAGVLSGDQDTGDLVLLDVCPLTLGIETVGGVMTKLIPRNTVVPTKKSQIFSTASDNQPTVTIKVYEGERPLTKDNHLLGTFDLTGIPPAPRGVPQIEVTFEIDVNGILRVTAEDKGTGNKNKITITNDQNRLTPEEIERMVNDAEKFAEEDKKLKERIDTRNELESYAYSLKNQIGDKEKLGGKLSSEDKETMEKAVEEKIEWLESHQDADIEDFKAKKKELEEIVQPIISKLYGSAGPPPTGEEDTAEKDELSpecifications
| heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | |
| Polyclonal | |
| Mouse polyclonal antibody raised against a full-length recombinant HSPA5. | |
| HSPA5 | |
| BIP/FLJ26106/GRP78/MIF2 | |
| Mouse | |
| 50 μL | |
| Yes | |
| 3309 | |
| Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing. |
| ELISA, Western Blot | |
| Unconjugated | |
| 50% glycerol | |
| BC020235 | |
| HSPA5 | |
| HSPA5 (AAH20235.1, 19 a.a. ∼ 654 a.a) full-length recombinant protein with GST tag. | |
| RUO | |
| Primary | |
| Human | |
| Serum |
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