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inhibitor of DNA binding 4, dominant negative helix-loop-helix protein, Mouse, Purified MaxPab™ Polyclonal Antibody, Abnova™
Mouse polyclonal antibody raised against a full-length human ID4 protein.
Brand: Abnova H00003400-B01P.50ug
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Description
Transcription factors containing a basic helix-loop-helix (bHLH) motif regulate expression of tissue-specific genes in a number of mammalian and insect systems. DNA-binding activity of the bHLH proteins is dependent on formation of homo- and/or heterodimers. Dominant-negative HLH proteins encoded by Id-related genes, such as ID4, also contain the HLH-dimerization domain but lack the DNA-binding basic domain. Consequently, Id proteins inhibit binding to DNA and transcriptional transactivation by heterodimerization with bHLH proteins (Pagliuca et al., 1995 [PubMed 7665172]).[supplied by OMIM
Sequence: MKAVSPVRPSGRKAPSGCGGGELALRCLAEHGHSLGGSAAAAAAAAAARCKAAEAAADEPALCLQCDMNDCYSRLRRLVPTIPPNKKVSKVEILQHVIDYILDLQLALETHPALLRQPPPPAPPHHPAGTCPAAPPRTPLTALNTDPAGAVNKQGDSILCRSpecifications
| inhibitor of DNA binding 4, dominant negative helix-loop-helix protein | |
| Polyclonal | |
| Mouse polyclonal antibody raised against a full-length human ID4 protein. | |
| ID4 | |
| IDB4/bHLHb27 | |
| Mouse | |
| Affinity Purified | |
| RUO | |
| Primary | |
| Human | |
| Antibody |
| Western Blot | |
| Unconjugated | |
| PBS with no preservative; pH 7.4 | |
| NM_001546 | |
| ID4 | |
| ID4 (NP_001537, 1 a.a. ∼ 161 a.a) full-length human protein. | |
| 50 μg | |
| Transcription Regulation | |
| 3400 | |
| Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing. | |
| IgG |
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