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  6. 16199784

isocitrate dehydrogenase 2 (NADP+), mitochondrial, Mouse, Polyclonal Antibody, Abnova™

Mouse polyclonal antibody raised against a partial recombinant IDH2.

Brand:  Abnova H00003418-A01.50uL

Product Code. 16199784

  • € 242.00 / 50µL

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Description

Description

Isocitrate dehydrogenases catalyze the oxidative decarboxylation of isocitrate to 2-oxoglutarate. These enzymes belong to two distinct subclasses, one of which utilizes NAD(+) as the electron acceptor and the other NADP(+). Five isocitrate dehydrogenases have been reported: three NAD(+)-dependent isocitrate dehydrogenases, which localize to the mitochondrial matrix, and two NADP(+)-dependent isocitrate dehydrogenases, one of which is mitochondrial and the other predominantly cytosolic. Each NADP(+)-dependent isozyme is a homodimer. The protein encoded by this gene is the NADP(+)-dependent isocitrate dehydrogenase found in the mitochondria. It plays a role in intermediary metabolism and energy production. This protein may tightly associate or interact with the pyruvate dehydrogenase complex. [provided by RefSeq]

Sequence: HYREHQKGRPTSTNPIASIFAWTRGLEHRGKLDGNQDLIRFAQMLEKVCVETVESGAMTKDLAGCIHGLSNVKLNEHFLNTTDFLDTIKSNLDRALGR
Specifications

Specifications

isocitrate dehydrogenase 2 (NADP+), mitochondrial
Polyclonal
Mouse polyclonal antibody raised against a partial recombinant IDH2.
IDH2
ICD-M/IDH/IDHM/IDP/IDPM/mNADP-IDH
Mouse
50 μL
Yes
3418
Human
Serum
ELISA, Western Blot
Unconjugated
50% glycerol
NM_002168
IDH2
IDH2 (NP_002159, 354 a.a. ∼ 451 a.a) partial recombinant protein with GST tag.
RUO
Primary
This antibody cross-reacts with human IDH1.
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
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