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IFN-α (2b) Mouse anti-Human, NA/LE, Unlabeled, Clone: 7N4-1, BD

Product Code. 15826698
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Product Code. 15826698 Supplier BD Biosciences Supplier No. 551795

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Description

Mouse Monoclonal Antibody

The 7N4-1 antibody reacts with human IFN-α2b and to a lesser extent with IFN-α7. It does not react with IFN-α1 nor IFN-α4. IFN-α2b is one of the three variants of IFN-α2 that have been isolated from human cell lines. IFN-α2b is the variant predominantly produced by human leukocytes. Human IFN-α2b belongs to the IFN-α class of proteins also known as leukocyte interferons. IFN-α comprises a family of related but distinct proteins with molecular weights ranging from 16-27kDa with antiviral, antiproliferative and immunomodulatory activities. The IFN-α family is composed from as many as 14 different genes. The immunogen used to generate the 7N4-1 hybridoma was E. coli-expressed recombinant human IFN-α2b. This is a neutralizing antibody.

Host Species: Mouse
Clone: 7N4-1
Isotype: IgG1 κ
Species Reactivity: Human
Immunogen: E. coli-expressed recombinant human IFN-α2b

Functional Assay, Immunohistochemistry

TRUSTED_SUSTAINABILITY

Specifications

Antigen IFN-α (2b)
Applications Flow Cytometry
Classification Monoclonal
Clone 7N4-1
Concentration 1.0mg/mL
Conjugate Unconjugated
Description IFNa, IFNα
Formulation No azide/low endotoxin: Aqueous buffered solution containing no preservative, 0.2μm sterile filtered. Endotoxin level is ≤0.01 EU/μg (≤0.001 ng/μg) of protein as determined by the LAL assay.
Host Species Mouse
Immunogen E. coli-expressed recombinant human IFN-α2b
Purification Method Affinity Purified
Quantity 0.5 mg
Regulatory Status RUO
Research Discipline Immunology
Primary or Secondary Primary
Target Species Human
Content And Storage Store undiluted at 4°C
Isotype IgG1 κ
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For Research Use Only.

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