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IL-17A Rat anti-Mouse, Unlabeled, Clone: TC11-18H10, BD
Rat Monoclonal Antibody
Brand: BD Biosciences 555068
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Description
The TC11-18H10 antibody reacts with recombinant and natural mouse IL-17A proteins. IL-17A, also known as CTLA-8, is a T cell-derived cytokine that promotes inflammatory responses. Mouse IL-17A is a proinflammatory cytokine that can induce the release of IL-6 by mouse stromal cells. It has been shown to support the growth of hemopoietic progenitors in vitro; it can also stimulate granulopoiesis in vivo. The TC11-18H10 antibody has been reported to neutralize IL-17A activity. Recent studies have shown that IL-17A is produced by a unique subset of Th17 cells that develop along a pathway distinct from the Th1- and Th2- cell differentiation pathways. The mouse IL-17A cDNA was isolated from a cDNA library generated from TCRαβ+CD4-CD8-thymocytes.
Blocking Assay, ELISA, Intracellular Staining, Western Blotting
Specifications
| IL-17A | |
| Monoclonal | |
| 0.5mg/mL | |
| Aqueous buffered solution containing ≤0.09% sodium azide. | |
| Recombinant Mouse IL-17 Protein | |
| 0.5 mg | |
| Immunology | |
| Mouse | |
| IgG1 κ |
| Blocking Assay, ELISA, Flow Cytometry | |
| TC11-18H10 | |
| Unconjugated | |
| Rat | |
| Affinity Purified | |
| RUO | |
| Primary | |
| Store undiluted at 4°C |
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