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IL1B, Mouse, Polyclonal Antibody, Abnova™
Description
The protein encoded by this gene is a member of the interleukin 1 cytokine family. This cytokine is produced by activated macrophages as a proprotein, which is proteolytically processed to its active form by caspase 1 (CASP1/ICE). This cytokine is an important mediator of the inflammatory response, and is involved in a variety of cellular activities, including cell proliferation, differentiation, and apoptosis. The induction of cyclooxygenase-2 (PTGS2/COX2) by this cytokine in the central nervous system (CNS) is found to contribute to inflammatory pain hypersensitivity. This gene and eight other interleukin 1 family genes form a cytokine gene cluster on chromosome 2. [provided by RefSeq
Specifications
Specifications
| Antigen | IL1B |
| Applications | ELISA, Western Blot |
| Classification | Polyclonal |
| Conjugate | Unconjugated |
| Description | Mouse polyclonal antibody raised against a partial recombinant IL1B. |
| Formulation | 50% glycerol |
| Gene | IL1B |
| Gene Accession No. | BC008678 |
| Gene Alias | IL-1/IL1-BETA/IL1F2 |
| Gene Symbols | IL1B |
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