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Description
FIB504 reacts with mouse integrin β7 subunit (130kDa) but also cross reacts with human integrin β7. Integrin β7 associates with α4 (CD49d) expressed on subsets of lymphocytes and thymus. It also associates with αIEL (CD103) expressed on T cells adjacent to mucosal epithelium and intraepithelial lymphocytes. Integrin β7 plays an important role in the adhesion of leukocytes to endothelial cells promoting the transmigration of leukocytes to extravascular spaces during the inflammatory response.
Host Species: Rat
Clone: FIB504
Isotype: IgG2a κ
Species Reactivity: Human
Flow Cytometry
Specifications
| Integrin β7 | |
| Monoclonal | |
| PE | |
| Rat | |
| Affinity Purified | |
| RUO | |
| Primary | |
| Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze. |
| Flow Cytometry | |
| FIB504 | |
| Aqueous buffered solution containing BSA and ≤0.09% sodium azide. | |
| Mouse T lymphoma line TK1 | |
| 100 Tests | |
| Immunology | |
| Human | |
| IgG2a κ |
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Product Title
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