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Ly-6D Rat anti-Mouse, Unlabeled, Clone: 49-H4, BD

Product Code. 15828898
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Product Code. 15828898 Supplier BD Biosciences Supplier No. 557360

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Description

Rat Monoclonal Antibody

The 49-H4 antibody reacts with the ThB antigen (Ly-6D), which is a 15kDa GPI-anchored protein of the Ly-6 multigene family. ThB has been detected on cortical thymocytes, small sIg- Thy-1- and sIg+ lymphoid cells in the bone marrow, thymic medullary epithelial cells, all epidermal layers (except the stratum corneum), and on peripheral B lymphocytes, but not on peripheral T lymphocytes. It has been noted that there is strain-to-strain variation in the expression of the ThB antigen on splenic B cells, those of strains with the Ly-6.2 haplotype (e.g., AKR, C57BL, DBA/2, SJL, SWR) stain more intensely with anti- ThB reagents than those of Ly-6.1 strains (e.g., A, BALB/c, CBA, C3H/He, NZB), and B cells of hybrids of Ly-6.1 and Ly-6.2 strains stain with intermediate intensity. The proportions of the ThB+ B cells and thymocytes do not differ significantly among strains.

Host Species: Rat
Clone: 49-H4
Isotype: IgG2c
Cross Reactivity: Mouse

Flow Cytometry, Immunohistochemistry (Frozen), Immunoprecipitation

TRUSTED_SUSTAINABILITY

Specifications

Antigen Ly-6D
Applications Flow Cytometry
Classification Monoclonal
Clone 49-H4
Concentration 0.5mg/mL
Conjugate Unconjugated
Description Lymphocyte antigen 6 complex, locus D; Thb; Thymocyte B-cell antigen; Ly-61
Formulation Aqueous buffered solution containing ≤0.09% sodium azide.
Host Species Rat
Immunogen BALB/c mouse plasmacytoma MOPC-104E
Purification Method Affinity Purified
Quantity 0.1 mg
Regulatory Status RUO
Research Discipline Immunology
Primary or Secondary Primary
Target Species Mouse
Content And Storage Store undiluted at 4°C
Isotype IgG2c κ
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For Research Use Only.

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