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Description
The M3/84 antibody reacts with the 110kDa Mac-3 antigen expressed on mouse mononuclear phagocytes. Surface expression of the 92 to 110kDa glycoprotein antigen increases during differentiation of monocytes to activated peritoneal macrophages. The M3/84 mAb can detect CD107b antigen on tissue macrophages, thioglycollate-elicited peritoneal macrophages, and some myeloid cell lines, but not on lymphocytes or monocytes. In the bone marrow, very few cells display CD107b antigen on the surface, but a large proportion express cytoplasmic CD107b. The M3/84 antibody has also been reported to stain dendritic cells and endothelium in sections of thymus (both medulla and cortex), lymph nodes, spleen (white pulp), and gut-associated lymphoid tissue.
Specifications
| Mac-3 | |
| Monoclonal | |
| 31.25μg/mL | |
| CD107b; Lamp2; LAMP-2; Lysosome-associated membrane glycoprotein 2; LGP-B | |
| Rat | |
| Affinity Purified | |
| RUO | |
| Primary | |
| Store undiluted at 4°C |
| Flow Cytometry | |
| M3/84 | |
| Unconjugated | |
| Aqueous buffered solution containing BSA, goat serum, and ≤0.09% sodium azide. | |
| Mouse C57Bl/6 peritoneal exudate cells | |
| 1 mL | |
| Immunology | |
| Mouse | |
| IgG1 κ |
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Product Title
For Research Use Only.
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