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CD276 Rat anti-Mouse, PE, Clone: MIH32, BD
Rat Monoclonal Antibody
Brand: BD Biosciences 562357
Description
The MIH32 monoclonal antibody specifically binds to CD276, also known as B7-H3 (B7 homolog 3). CD276 is a type I transmembrane glycoprotein and member of the B7-family of regulatory proteins. The expression of B7-H3 can be induced on T cells, natural killer (NK) cells and antigen presenting cells. B7-H3 is up-regulated during the differentiation of monocytes into dendritic cells or during the interaction between dendritic cells and regulatory T cells. In addition, B7-H3 is found to be expressed on fibroblasts, fibroblast-like synoviocytes and epithelial cells. CD276 (B7-H3) can function as a positive or a negative regulator of T responses.
Specifications
| CD276 | |
| Monoclonal | |
| 0.2mg/mL | |
| Cd276; B7-H3; B7 homolog 3; B7h3; B7RP-2; Costimulatory molecule | |
| Rat | |
| Affinity Purified | |
| RUO | |
| Mouse | |
| IgG2a κ |
| Flow Cytometry | |
| MIH32 | |
| PE | |
| Aqueous buffered solution containing ≤0.09% sodium azide. | |
| Mouse B7-H3 Transfected Cell Line | |
| 0.1 mg | |
| Primary | |
| Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze. |
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