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Ly-6G Rat anti-Mouse, PE-CF594, Clone: 1A8, BD
Description
The 1A8 monoclonal antibody specifically binds to Ly-6G, a 21-25-kDa glycosyolphosphatidylinositol-anchored protein. In the bone marrow, Ly-6G is expressed on the majority of the largest cells, which are predominantly granulocytes, and not on lymphoid or erythroid cells. In the periphery, it is expressed on granulocytes. The RB6-8C5 monoclonal antibody recognizes both Ly-6G and Ly-6C and blocks the binding of mAb 1A8 to Ly-6G.
This antibody is conjugated to BD Horizon™ PE-CF594, which has been developed exclusively by BD Biosciences as a better alternative to PE-Texas Red™. PE-CF594 excites and emits at similar wavelengths to PE-Texas Red™ yet exhibits improved brightness and spectral characteristics. Due to PE having maximal absorption peaks at 496nm and 564nm, PE-CF594 can be excited by the blue (488-nm), green (532-nm) and yellow-green (561-nm) lasers and can be detected with the same filter set as PE-Texas Red™ (eg 610/20-nm filter).
Specifications
Specifications
| Antigen | Ly-6G |
| Applications | Flow Cytometry |
| Classification | Monoclonal |
| Clone | 1A8 |
| Concentration | 0.2mg/mL |
| Conjugate | PE-CF594 |
| Description | Ly6g; Lymphocyte antigen 6G; Lymphocyte antigen 6 complex, locus G; Gr1 |
| Formulation | Aqueous buffered solution containing BSA and ≤0.09% sodium azide. |
| Host Species | Rat |
| Immunogen | Ly-6G-transfected EL4J cell line |
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