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myelin protein zero-like 2, Mouse, Purified MaxPab™ Polyclonal Antibody, Abnova™

Mouse polyclonal antibody raised against a full-length human MPZL2 protein.

Brand:  Abnova H00010205-B01P.50ug

Product Code. 16172096

  • € 349.00 / 50µg

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Description

Description

Thymus development depends on a complex series of interactions between thymocytes and the stromal component of the organ. Epithelial V-like antigen (EVA) is expressed in thymus epithelium and strongly downregulated by thymocyte developmental progression. This gene is expressed in the thymus and in several epithelial structures early in embryogenesis. It is highly homologous to the myelin protein zero and, in thymus-derived epithelial cell lines, is poorly soluble in nonionic detergents, strongly suggesting an association to the cytoskeleton. Its capacity to mediate cell adhesion through a homophilic interaction and its selective regulation by T cell maturation might imply the participation of EVA in the earliest phases of thymus organogenesis. The protein bears a characteristic V-type domain and two potential N-glycosylation sites in the extracellular domain; a putative serine phosphorylation site for casein kinase 2 is also present in the cytoplasmic tail. Two transcript variants encoding the same protein have been found for this gene. [provided by RefSeq

Sequence: MYGKSSTRAVLLLLGIQLTALWPIAAVEIYTSRVLEAVNGTDARLKCTFSSFAPVGDALTVTWNFRPLDGGPEQFVFYYHIDPFQPMSGRFKDRVSWDGNPERYDASILLWKLQFDDNGTYTCQVKNPPDVDGVIGEIRLSVVHTVRFSEIHFLALAIGSACALMIIIVIVVVLFQHYRKKRWAERAHKVVEIKSKEEERLNQEKKVSVYLEDTD
Specifications

Specifications

myelin protein zero-like 2
Polyclonal
Mouse polyclonal antibody raised against a full-length human MPZL2 protein.
MPZL2
EVA/EVA1
Mouse
Affinity Purified
RUO
Primary
Human
Antibody
Western Blot
Unconjugated
PBS with no preservative; pH 7.4
NM_005797.2
MPZL2
MPZL2 (NP_005788.1, 1 a.a. ∼ 215 a.a) full-length human protein.
50 μg
Cell Adhesion
10205
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
IgG
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