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nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 1, Mouse, Polyclonal Antibody, Abnova™

Mouse polyclonal antibody raised against a partial recombinant NFATC1.

Brand:  Abnova H00004772-A01.50uL

Product Code. 16121865

  • € 242.00 / 50µL

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Description

Description

The product of this gene is a component of the nuclear factor of activated T cells DNA-binding transcription complex. This complex consists of at least two components: a preexisting cytosolic component that translocates to the nucleus upon T cell receptor (TCR) stimulation, and an inducible nuclear component. Proteins belonging to this family of transcription factors play a central role in inducible gene transcription during immune response. The product of this gene is an inducible nuclear component. It functions as a major molecular target for the immunosuppressive drugs such as cyclosporin A. Five transcript variants encoding distinct isoforms have been identified for this gene. Different isoforms of this protein may regulate inducible expression of different cytokine genes. [provided by RefSeq

Sequence: IKTEPTDDYEPAPTCGPVSQGLSPLPRPYYSQQLAMPPDPSSCLVAGFPPCPQRSTLMPAAPGVSPKLHDLSPAAYTKGVASPGHCHLGLPQPAGEAPAVQDVPRPVATH
Specifications

Specifications

nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 1
Polyclonal
Mouse polyclonal antibody raised against a partial recombinant NFATC1.
NFATC1
MGC138448/NF-ATC/NFAT2/NFATc
Mouse
50 μL
Transcription Regulation
4772
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
ELISA, Western Blot
Unconjugated
50% glycerol
NM_006162
NFATC1
NFATC1 (NP_006153, 701 a.a. ∼ 810 a.a) partial recombinant protein with GST tag.
RUO
Primary
Human
Serum
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