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protocadherin gamma subfamily B, 7, Mouse, Polyclonal Antibody, Abnova™

Mouse polyclonal antibody raised against a partial recombinant PCDHGB7.

Brand:  Abnova H00056099-A01.50uL

Product Code. 16138606

  • € 242.00 / 50µL

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Description

Description

This gene is a member of the protocadherin gamma gene cluster, one of three related clusters tandemly linked on chromosome five. These gene clusters have an immunoglobulin-like organization, suggesting that a novel mechanism may be involved in their regulation and expression. The gamma gene cluster includes 22 genes divided into 3 subfamilies. Subfamily A contains 12 genes, subfamily B contains 7 genes and 2 pseudogenes, and the more distantly related subfamily C contains 3 genes. The tandem array of 22 large, variable region exons are followed by a constant region, containing 3 exons shared by all genes in the cluster. Each variable region exon encodes the extracellular region, which includes 6 cadherin ectodomains and a transmembrane region. The constant region exons encode the common cytoplasmic region. These neural cadherin-like cell adhesion proteins most likely play a critical role in the establishment and function of specific cell-cell connections in the brain. Alternative splicing has been described for the gamma cluster genes. [provided by RefSeq

Sequence: TLDRETQSAHHLVLTALDGGDPPRSGTAQIRILVIDANDNPPVFSQDVYRVSLREDVPPGTSILRVKATDQDEGINSEITYSFFGVADKAQHV
Specifications

Specifications

protocadherin gamma subfamily B, 7
Polyclonal
Mouse polyclonal antibody raised against a partial recombinant PCDHGB7.
PCDHGB7
ME6/PCDH-GAMMA-B7
Mouse
50 μL
Cell Adhesion
Primary
Human
Serum
ELISA, Western Blot
Unconjugated
50% glycerol
NM_018927
PCDHGB7
PCDHGB7 (NP_061750, 199 a.a. ∼ 291 a.a) partial recombinant protein with GST tag.
RUO
Yes
56099
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
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