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platelet factor 4, Rabbit, Purified MaxPab™ Polyclonal Antibody, Abnova™
Description
Platelet factor-4 is a 70-amino acid protein that is released from the alpha-granules of activated platelets and binds with high affinity to heparin. Its major physiologic role appears to be neutralization of heparin-like molecules on the endothelial surface of blood vessels, thereby inhibiting local antithrombin III activity and promoting coagulation. As a strong chemoattractant for neutrophils and fibroblasts, PF4 probably has a role in inflammation and wound repair (Eisman et al., 1990 [PubMed 1695112]).[supplied by OMIM
Specifications
Specifications
| Antigen | platelet factor 4 |
| Applications | Western Blot |
| Classification | Polyclonal |
| Conjugate | Unconjugated |
| Description | Rabbit polyclonal antibody raised against a full-length human PF4 protein. |
| Formulation | PBS with no preservative; pH 7.4 |
| Gene | PF4 |
| Gene Accession No. | NM_002619 |
| Gene Alias | CXCL4/MGC138298/SCYB4 |
| Gene Symbols | PF4 |
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