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runt-related transcription factor 3 (B01), Mouse anti-Human, Polyclonal Antibody, Abnova™
Description
This gene encodes a member of the runt domain-containing family of transcription factors. A heterodimer of this protein and a beta subunit forms a complex that binds to the core DNA sequence 5'-PYGPYGGT-3' found in a number of enhancers and promoters, and can either activate or suppress transcription. It also interacts with other transcription factors. It functions as a tumor suppressor, and the gene is frequently deleted or transcriptionally silenced in cancer. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq]
Specifications
Specifications
| Antigen | runt-related transcription factor 3 |
| Applications | Immunofluorescence, Immunohistochemistry (PFA fixed), Western Blot |
| Classification | Polyclonal |
| Conjugate | Unconjugated |
| Description | Mouse polyclonal antibody raised against a full-length human RUNX3 protein. |
| Formulation | No additive |
| Gene | RUNX3 |
| Gene Accession No. | NM_001031680.2 |
| Gene Alias | AML2/CBFA3/FLJ34510/MGC16070/PEBP2aC |
| Gene Symbols | RUNX3 |
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