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TNF Mouse anti-Human, APC, Clone: MAb11, BD

Product Code. 15871629
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25 μg
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Each
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15871629 25 μg Each
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Product Code. 15871629 Supplier BD Biosciences Supplier No. 562084

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Mouse Monoclonal Antibody

The MAb11 monoclonal antibody specifically binds to human tumor necrosis factor (TNF, also known as TNF- α ) protein. TNF is an efficient juxtacrine, paracrine and endocrine mediator of inflammatory and immune functions. It regulates the growth and differentiation of a variety of cell types. TNF is cytotoxic for transformed cells when in conjunction with IFN- γ. It is secreted by activated monocytes/macrophages and other cells such as B cells, T cells and fibroblasts. The immunogen used to generate the MAb11 hybridoma was recombinant human TNF. The MAb11 antibody has been reported to crossreact with Rhesus Macaque TNF.

TRUSTED_SUSTAINABILITY

Specifications

Antigen TNF
Applications Flow Cytometry
Classification Monoclonal
Clone MAb11
Concentration 0.2mg/mL
Conjugate APC
Formulation Aqueous buffered solution containing ≤0.09% sodium azide.
Host Species Mouse
Immunogen Recombinant Human TNF
Purification Method Affinity Purified
Quantity 25 μg
Regulatory Status RUO
Primary or Secondary Primary
Target Species Human
Content And Storage Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Isotype IgG1 κ
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