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TNF Mouse anti-Human, APC, Clone: MAb11, BD
Description
The MAb11 monoclonal antibody specifically binds to human tumor necrosis factor (TNF, also known as TNF- α ) protein. TNF is an efficient juxtacrine, paracrine and endocrine mediator of inflammatory and immune functions. It regulates the growth and differentiation of a variety of cell types. TNF is cytotoxic for transformed cells when in conjunction with IFN- γ. It is secreted by activated monocytes/macrophages and other cells such as B cells, T cells and fibroblasts. The immunogen used to generate the MAb11 hybridoma was recombinant human TNF. The MAb11 antibody has been reported to crossreact with Rhesus Macaque TNF.
Specifications
Specifications
| Antigen | TNF |
| Applications | Flow Cytometry |
| Classification | Monoclonal |
| Clone | MAb11 |
| Concentration | 0.2mg/mL |
| Conjugate | APC |
| Formulation | Aqueous buffered solution containing ≤0.09% sodium azide. |
| Host Species | Mouse |
| Immunogen | Recombinant Human TNF |
| Purification Method | Affinity Purified |
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