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TRA-1-81 Antigen Mouse anti-Human, Alexa Fluor 647, Clone: TRA-1-81, BD

Product Code. 15840499
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100 Tests
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Product Code. 15840499 Supplier BD Biosciences Supplier No. 560793

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Mouse Monoclonal Antibody

The TRA-1-81 monoclonal antibody reacts with a pluripotent-stem-cell-specific epitope on a high-molecular-weight transmembrane glycoprotein. The TRA-1-81 antigen is an epitope on the same keratan sulfate core molecule, podocalyxin, as 4 other distinct antigens on tumor-derived cell lines, TRA-1-60, GCTM2, K4, and K21. The expression of TRA-1-81 antigen is stage-specific and can be used to characterize embryonic cells and monitor their differentiation. The antigen is found on teratocarcinoma (embryonal carcinoma or EC), embryonic inner cell mass (but not morula or trophoblast), and embryonic stem (ES) cells. As human EC and ES cells undergo differentiation, expression of TRA-1-81 antigen is lost.

TRUSTED_SUSTAINABILITY

Specifications

Antigen TRA-1-81 Antigen
Applications Flow Cytometry
Classification Monoclonal
Clone TRA-1-81
Conjugate Alexa Fluor 647
Formulation Aqueous buffered solution containing BSA and ≤0.09% sodium azide.
Host Species Mouse
Immunogen Human Embryonal Carcinoma Cell Line
Purification Method Affinity Purified
Quantity 100 Tests
Regulatory Status RUO
Primary or Secondary Primary
Target Species Human
Content And Storage Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Isotype IgM κ
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