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TRA-1-81 Antigen Mouse anti-Human, Alexa Fluor 647, Clone: TRA-1-81, BD
Description
The TRA-1-81 monoclonal antibody reacts with a pluripotent-stem-cell-specific epitope on a high-molecular-weight transmembrane glycoprotein. The TRA-1-81 antigen is an epitope on the same keratan sulfate core molecule, podocalyxin, as 4 other distinct antigens on tumor-derived cell lines, TRA-1-60, GCTM2, K4, and K21. The expression of TRA-1-81 antigen is stage-specific and can be used to characterize embryonic cells and monitor their differentiation. The antigen is found on teratocarcinoma (embryonal carcinoma or EC), embryonic inner cell mass (but not morula or trophoblast), and embryonic stem (ES) cells. As human EC and ES cells undergo differentiation, expression of TRA-1-81 antigen is lost.
Specifications
Specifications
| Antigen | TRA-1-81 Antigen |
| Applications | Flow Cytometry |
| Classification | Monoclonal |
| Clone | TRA-1-81 |
| Conjugate | Alexa Fluor 647 |
| Formulation | Aqueous buffered solution containing BSA and ≤0.09% sodium azide. |
| Host Species | Mouse |
| Immunogen | Human Embryonal Carcinoma Cell Line |
| Purification Method | Affinity Purified |
| Quantity | 100 Tests |
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