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ubiquitin-like with PHD and ring finger domains 1, Mouse, Clone: 3B12, Abnova™
Mouse monoclonal antibody raised against a partial recombinant UHRF1.
Brand: Abnova H00029128-M02.100ug
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Description
This gene encodes a member of a subfamily of RING-finger type E3 ubiquitin ligases. The protein binds to specific DNA sequences, and recruits a histone deacetylase to regulate gene expression. Its expression peaks at late G1 phase and continues during G2 and M phases of the cell cycle. It plays a major role in the G1/S transition by regulating topoisomerase IIalpha and retinoblastoma gene expression, and functions in the p53-dependent DNA damage checkpoint. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq
Sequence: WNEVLASLKDRPASGSPFQLFLSKVEETFQCICCQELVFRPITTVCQHNVCKDCLDRSFRAQVFSCPACRYDLGRSYAMQVNQPLQTVLNQLFPGYGNGRSpecifications
| ubiquitin-like with PHD and ring finger domains 1 | |
| Monoclonal | |
| Unconjugated | |
| PBS with no preservative; pH 7.4 | |
| NM_013282 | |
| UHRF1 | |
| UHRF1 (NP_037414, 694 a.a. ∼ 793 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa. | |
| 100 μg | |
| Transcription Regulation | |
| Primary | |
| Human | |
| Antibody |
| ELISA, Immunofluorescence, Western Blot | |
| 3B12 | |
| Mouse monoclonal antibody raised against a partial recombinant UHRF1. | |
| UHRF1 | |
| FLJ21925/ICBP90/MGC138707/Np95/RNF106/hNP95 | |
| Mouse | |
| Affinity Purified | |
| RUO | |
| Yes | |
| 29128 | |
| Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing. | |
| IgG1 κ |
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