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VASP Mouse, Unlabeled, Clone: 43, BD
Mouse Monoclonal Antibody
€ 249.85 - € 323.14
Specifications
| Antigen | VASP |
|---|---|
| Clone | 43 |
| Concentration | 250μg/mL |
| Applications | Western Blot |
| Classification | Monoclonal |
| Product Code | Brand | Quantity | Price | Quantity & Availability | |||||
|---|---|---|---|---|---|---|---|---|---|
| Product Code | Brand | Quantity | Price | Quantity & Availability | |||||
|
15825469
|
BD Biosciences
610447 |
50 μg |
 € 251.00 € 249.85 / 1 set Save € 1.15 0.46% Off |
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|
15835469
|
BD Biosciences
610448 |
150 μg |
€ 325.00 € 323.14 / 1 set Save € 1.86 0.57% Off |
Please sign in to purchase this item. Need a web account? Register with us today! | |||||
Description
Vasodilator-stimulated phosphoprotein (VASP), a substrate for cAMP- and cGMP-dependent kinases, is associated with actin filaments, focal adhesions, and dynamic membrane regions. VASP is composed of several distinct domains: a central L-proline-rich domain contains a GPPPPP motif as a single copy and as a three-fold tandem repeat, as well as three conserved phosphorylation sites for cyclic nucleotide-dependent protein kinases (Ser157, Ser239, and Thr278). A C-terminal domain contains a repetitive mixed-charge cluster which is predicted to form an α-helix. The C-terminal domain appears to be responsible for anchoring at focal adhesion sites. VASP has been shown to be a ligand for profilins. Profilins bind to the poly-L-proline motifs of VASP and it is postulated that these two molecules act in concert to convey signal transduction to actin filament formation.
Immunofluorescence, Immunoprecipitation, Western Blotting
Specifications
| VASP | |
| 250μg/mL | |
| Monoclonal | |
| Mouse | |
| Cell Biology | |
| Aqueous buffered solution containing BSA, glycerol, and ≤0.09% sodium azide. | |
| IgG1 | |
| Affinity Purified |
| 43 | |
| Western Blot | |
| Unconjugated | |
| RUO | |
| Canine, Human | |
| Aqueous buffered solution containing BSA, glycerol, and ≤0.09% sodium azide. | |
| Primary | |
| Store undiluted at -20°C. |
For Research Use Only.
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