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Invitrogen™ AP2M1 Polyclonal Antibody
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Rabbit Polyclonal Antibody

Brand:  Invitrogen™ PA5111653

Product Code. 17119573

  • € 618.00 / 100µL

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Description

Description

Immunogen sequence: LLMSPQGQVL SAHVSGRVVM KSYLSGMPEC KFGMNDKIVI EKQGKGTADE TSKSGKQSIA IDDCTF Highest antigen sequence indentity to the following orthologs: Rat - 100%, Mouse - 100%.

The heterotetrameric coat assembly protein complex, also known as the adaptor-related protein complex 2 (AP-2), belongs to the adaptor complexes medium subunits family. The mu 1 subunit of the AP-2 complex (AP2M1) is required for the activity of a vacuolar ATPase, which is responsible for proton pumping occurring in the acidification of endosomes and lysosomes. AP2M1 has also been shown to associate with the HIV-1 protein Nef, suggesting that Nef may use AP-2 complex to enhance the rate of endocytosis of both CD4 and class I MHC. AP2M1 may also play an important role in regulating the intracellular trafficking and function of cytotoxic T-lymphocyte associated (CTLA)-4 protein. At least two isoforms of AP2M1 are known to exist.
TRUSTED_SUSTAINABILITY
Specifications

Specifications

AP2M1
Polyclonal
Unconjugated
AP2M1
adapter-related protein complex 2 mu subunit; adapter-related protein complex 2 subunit mu; adaptin-mu2; Adaptor protein complex AP-2 subunit mu; adaptor related protein complex 2 mu 1 subunit; adaptor related protein complex 2 subunit mu 1; adaptor related protein complex 2, mu 1 subunit; adaptor-related protein complex 2 subunit mu; adaptor-related protein complex 2, mu 1 subunit; AP-2 complex subunit mu; AP-2 mu 2 chain; AP-2 mu chain; Ap2m1; AP50; Clapm1; clathrin adaptor complex AP2, mu subunit; Clathrin assembly protein complex 2 medium chain; clathrin assembly protein complex 2 mu medium chain; clathrin coat adaptor protein AP50; Clathrin coat assembly protein AP50; Clathrin coat-associated protein AP50; clathrin-associated/assembly/adaptor protein, medium 1; coat assembly protein complex 50 kD; HA2 50 kDA subunit; KIAA0109; mu2; Mu2-adaptin; Plasma membrane adaptor AP-2 50 kDa protein; plasma membrane adaptor AP-2 50kDA protein; QtsA-16673; unnamed protein product
Rabbit
Antigen affinity chromatography
RUO
1173
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Liquid
Immunocytochemistry
0.2 mg/mL
PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
Q96CW1
AP2M1
Recombinant Protein corresonding to Human AP2M1. Recombinant protein control fragment (Product #RP-107721).
100 μL
Primary
Human
Antibody
IgG
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