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Invitrogen™ APAF1 Monoclonal Antibody (2H9G5)
Mouse Monoclonal Antibody
Brand: Invitrogen™ MA548372
This item is not returnable.
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Description
APAF1 Monoclonal Antibody for Western Blot, Flow, ELISA
APAF1 gene encodes a cytoplasmic protein that initiates apoptosis. This protein contains several copies of the WD-40 domain, a caspase recruitment domain (CARD), and an ATPase domain (NB-ARC). Upon binding cytochrome c and dATP, this protein forms an oligomeric apoptosome. The apoptosome binds and cleaves caspase 9 preproprotein, releasing its mature, activated form. Activated caspase 9 stimulates the subsequent caspase cascade that commits the cell to apoptosis. Alternative splicing results in several transcript variants encoding different isoforms.
Specifications
| APAF1 | |
| Monoclonal | |
| 1 mg/mL | |
| PBS with 0.05% sodium azide | |
| O14727 | |
| APAF1 | |
| Purified recombinant fragment of human APAF1 (AA: 1138-1237) expressed in E. Coli. | |
| 100 μg | |
| Primary | |
| Human | |
| Antibody | |
| IgG2b |
| ELISA, Flow Cytometry, Western Blot | |
| 2H9G5 | |
| Unconjugated | |
| APAF1 | |
| 6230400I06Rik; APAF1; APAF-1; Apaf1l; apoptotic peptidase activating factor 1; apoptotic protease activating factor 1; apoptotic protease-activating factor 1; CED4; DKFZp781B1145; fog; forebrain overgrowth; KIAA0413; mKIAA0413 | |
| Mouse | |
| Protein G | |
| RUO | |
| 317 | |
| Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. | |
| Liquid |
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