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Invitrogen™ APBB2 Polyclonal Antibody

Description
Immunogen sequence: SEKLEGKEPH PQDSSSCEIL PSQPRRTKSF LNYYADLETS ARELEQNRGN HHGTAEEKSQ PVQGQASTII GNGDLLLQKP NRPQSSPEDG QVATVSSSPE TKKDHPKTGA KTDCALHRIQ NLAPS Highest antigen sequence identity to the following orthologs: Mouse - 85%, Rat - 23%.
The protein encoded by this gene interacts with the cytoplasmic domains of amyloid beta precursor protein and amyloid beta precursor-like protein 2. This protein contains two phosphotyrosine binding domains, which are thought to function in signal transduction. Polymorphisms in this gene have been associated with Alzheimer's disease. Alternative splicing results in multiple transcript variants.
Specifications
Specifications
| Antigen | APBB2 |
| Applications | Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry |
| Classification | Polyclonal |
| Concentration | 0.2 mg/mL |
| Conjugate | Unconjugated |
| Formulation | PBS with 40% glycerol and 0.02% sodium azide; pH 7.2 |
| Gene | Apbb2 |
| Gene Accession No. | Q92870 |
| Gene Alias | 2310007D03Rik; amyloid beta (A4) precursor protein-binding, family B, member 2; amyloid beta (A4) precursor protein-binding, family B, member 2 (Fe65-like); amyloid beta A4 precursor protein-binding family B member 2; amyloid beta A4 precursor protein-binding, family B, member 2; amyloid beta precursor protein binding family B member 2; amyloid beta precursor protein-binding family B member 2; amyloid-beta A4 precursor protein-binding family B member 2; Apbb2; FE65L; FE65L1; Fe65-like 1; Protein Fe65-like 1; RGD1562438; Rirl1; TR2L; Zfra; zinc finger-like protein |
| Gene Symbols | Apbb2 |
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