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  6. APC1 Rabbit anti-Human, Mouse, Rat, Polyclonal, Proteintech

APC1 Rabbit anti-Human, Mouse, Rat, Polyclonal, Proteintech

Product Code. p-7209864 Shop All Proteintech Products
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150 μL
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20µL
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16851345 20 μL 20µL
16841345 150 μL 150µL
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Product Code. 16851345 Supplier Proteintech Supplier No. 217481AP20UL

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Description

Rabbit Polyclonal Antibody

Cell cycle regulated protein ubiquitination and degradation within subcellular domains is thought to be essential for the normal progression of mitosis. APC1, also known as mitotic checkpoint regulator (MCPR), is a highly conserved component of the anaphase promoting complex/cyclosome (APC/C), a cell cycle-regulated E3 ubiquitin ligase that controls progression through mitosis and the G1 phase of the cell cycle. APC/C is responsible for degrading anaphase inhibitors, mitotic cyclins, and spindle-associated proteins ensuring that events of mitosis take place in proper sequence. The individual APC/C components mRNA and protein levels are expressed at approximately the same levels in most tissues and cell lines, suggesting that they perform their functions as part of a complex.

Specifications

Antigen APC1
Applications Immunohistochemistry (Paraffin), Western Blot
Classification Polyclonal
Concentration 0.39 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
Gene ANAPC1
Gene Accession No. P53995, Q9H1A4
Gene Alias ANAPC1, APC1, Mitotic checkpoint regulator, TSG24
Gene Symbols Anapc1
Host Species Rabbit
Immunogen APC1 Fusion Protein Ag13399
Purification Method Antigen Affinity Chromatography
Quantity 20 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 17222, 311412, 64682
Target Species Rat, Human, Mouse
Content And Storage -20°C
Product Type Antibody
Form Liquid
Isotype IgG
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