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Tocris Bioscience™ Apoptosis Activator 2

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Quantity:
10 mg
50 mg
Unit Size:
10mg
50mg
Description
Apoptosis activator; promotes the cytochrome c-dependent oligomerization of Apaf-1 into the mature apoptosome. Increases procaspase-9 processing and subsequent caspase-3 activation. Induces apoptosis in tumor cells (IC50 = 4 - 9 μM for leukemia cells) with weak or no effect on normal cell lines or those defective/deficient in Apaf-1, caspase-9 or caspase-3 activity (IC50 > 40 μM).
Spécification
Spécification
| Quantity | 50 mg |
| Formula Weight | 306.14 |
| Purity | >99% |
| Molecular Weight (g/mol) | 306.14 |
| Chemical Name or Material | Apoptosis Activator 2 |
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