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APP Monoclonal Antibody (OTI6F11), TrueMAB™, OriGene

Product Code. 17583002
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100 μL
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30µL
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17583002 100 μL 100µL
17503012 30 μL 30µL
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Product Code. 17583002 Supplier Origene Technologies Supplier No. TA505046

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Description

Mouse Monoclonal Antibody

Amyloid Precursor Protein (APP) or Amyloid beta protein functions as a cell surface kinesin I membrane receptor, mediating the axonal transport of beta-secretase and presenilin 1; APP is rapidly internalized via clathrin-coated pits. APP is important for neurite growth, neuronal adhesion and axonogenesis. Mutations in the APP gene can lead to Alzheimer disease 1 (AD1). This anitbody recognizes APP (b-APP770) with a MW of approximately 100kDa.

Specifications

Antigen APP
Applications Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot
Classification Monoclonal
Clone OTI6F11
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation PBS with 1% BSA, 50% glycerol and 0.02% sodium azide
Gene APP
Gene Accession No. P05067
Gene Alias AAA, ABETA, ABPP, AD1, APPI, CTFgamma, CVAP, PN-II, PN2, preA4
Gene Symbols APP
Host Species Mouse
Immunogen Full length human recombit protein of human APP produced in HEK23T cell.
Purification Method Affinity Chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 351
Target Species Human
Content And Storage -20° C, Avoid Freeze/Thaw Cycles
Product Type Antibody
Form Liquid
Isotype IgG2a
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