Aprotinin Monoclonal Antibody (21), Invitrogen™

Description

ABS 037-21-02 detects aprotinin in bovine samples. ABS 037-21-02 has successfully been used in ELISA applications. PBS based buffers are unsuitalbe for this assay and 0.2 M glycine sodium buffer, pH 8.8, is recommended for washing and dilution buffers. NOTE: Concentration is lot-dependent and can vary from 0.85-1.15 mg/mL

Aprotinin, also called bovine pancreatic trypsin inhibitor, is a single chain globular Kunitz-type serine proteinase inhibitor found in bovine pancreas, parotid gland and lung. It forms stable, enzymatically inactive complexes with trypsin, chymotrypsin, plasmin and kallikrein. Aprotinin has been used therapeutically as an antifibrinolytic agent under the name Trasylol (Bayer) to reduce blood loss during cardiopulmonary bypass surgery but this use has been associated with an increased frequency of acute renal injury.