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APS-2-79, MedChemExpress

Product Code. 16495837
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Product Code. 16495837 Supplier Medchem Express Supplier No. HY100627

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Description

MedChemExpress APS-2-79 is a KSR-dependent MEK antagonist. APS-2-79 inhibits ATPbiotin binding to KSR2 within the KSR2-MEK1 complexe with an IC50 of 120 nM. APS-2-79 makes the stabilization of the KSR inactive state antagonizes oncogenic Ras-MAPK signaling.

APS-2-79 is a KSR-dependent MEK antagonist. APS-2-79 inhibits ATPbiotin binding to KSR2 within the KSR2-MEK1 complexe with an IC50 of 120 nM. APS-2-79 makes the stabilization of the KSR inactive state antagonizes oncogenic Ras-MAPK signaling.

Specifications

Chemical Name or Material APS-2-79
CAS 2002381-25-9
Color Off-White
Purity Grade Notes Research
Molecular Formula C23H21N3O3
Quantity 5 mg
Solubility Information DMSO : 20 mg/mL (51.62 mM; Need ultrasonic)
SMILES CC1=CC(OC2=CC=CC=C2)=CC=C1NC3=NC=NC4=CC(OC)=C(OC)C=C43
Molecular Weight (g/mol) 387.43
Formula Weight 387.43
Percent Purity 99.48%
Grade Research
Physical Form Solid
For Use With (Application) Cancer-Kinase/protease
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Research purposes only

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