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Description
Arginase catalyzes the hydrolysis of arginine to ornithine and urea. At least two isoforms of mammalian arginase exists (types I and II) which differ in their tissue distribution, subcellular localization, immunologic crossreactivity and physiologic function. The type II isoform encoded by this gene, is located in the mitochondria and expressed in extra-hepatic tissues, especially kidney. The physiologic role of this isoform is poorly understood; it is thought to play a role in nitric oxide and polyamine metabolism. Transcript variants of the type II gene resulting from the use of alternative polyadenylation sites have been described.
Specifications
Specifications
| Antigen | ARG2 |
| Applications | Western Blot, Immunohistochemistry (Paraffin) |
| Classification | Polyclonal |
| Concentration | 0.39 mg/mL |
| Conjugate | Unconjugated |
| Formulation | PBS with 50% glycerol and 0.02% sodium azide; pH 7.3 |
| Gene | ARG2 |
| Gene Accession No. | O08691, O08701, P78540 |
| Gene Alias | ARG2, Arginase 2, mitochondrial, arginase, type II, Kidney type arginase, Non hepatic arginase, Type II arginase |
| Gene Symbols | ARG2 |
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Product Title
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