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Description
The antibody is specific to ARHGAP10.
GTPase activator for the small GTPases RhoA and Cdc42 by converting them to an inactive GDP-bound state. Essential for PTKB2 regulation of cytoskeletal organization via Rho family GTPases. Inhibits PAK2 proteolytic fragment PAK-2p34 kinase activity and changes its localization from the nucleus to the perinuclear region. Stabilizes PAK-2p34 thereby increasing stimulation of cell death.
Specifications
Specifications
| Antigen | ARHGAP10 |
| Applications | Immunohistochemistry (Paraffin), Western Blot |
| Classification | Polyclonal |
| Concentration | 0.4 mg/mL |
| Conjugate | Unconjugated |
| Formulation | PBS with 50% glycerol and 0.1% sodium azide; pH 7.3 |
| Gene | ARHGAP10 |
| Gene Accession No. | A1A4S6, Q6Y5D8 |
| Gene Alias | ARHGAP10, Graf related protein 2, GRAF2, PS GAP, PSGAP |
| Gene Symbols | Arhgap10 |
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Product Title
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