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Description
Antibody detects endogenous levels of total ARHGAP22.
GTPase-activating proteins (GAPs) accelerate the intrinsic rate of GTP hydrolysis of Ras-related proteins, resulting in down regulation of their active form. ARHGAP22 (Rho GTPase activating protein 22), also known as RHOGAP2, is a 698 amino acid protein that localizes to the cytoplasm, and contains one Rho-GAP domain and one PH domain. ARHGAP22 functions as a GTPase-activating protein for Rac 1 converting it to an inactive GDP-bound state and, through its interaction with ZNF161 (VEZF1), is thought to be useful in transcription regulation. Multiple isoforms of ARHGAP22 exist due to alternative splicing events.
Specifications
Specifications
| Antigen | ARHGAP22 |
| Applications | Western Blot, Immunocytochemistry |
| Classification | Polyclonal |
| Concentration | 1 mg/mL |
| Conjugate | Unconjugated |
| Formulation | PBS with 50% glycerol and 0.02% sodium azide; pH 7.4 |
| Gene | Arhgap22 |
| Gene Accession No. | Q7Z5H3, Q8BL80 |
| Gene Alias | Arhgap22; B230341L19Rik; p68RacGAP; RHG22; Rho GTPase activating protein 22; rho GTPase-activating protein 22; RHOGAP2; RhoGap22; Rho-type GTPase-activating protein 22 |
| Gene Symbols | Arhgap22 |
| Show More |
Product Title
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