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Invitrogen™ ARHGEF10 Polyclonal Antibody
Description
Immunogen sequence: RQPNSLSSEE PPTSEDQVGR EDSALARWAA DPANTAWMEN PEEAIYDDVP RENSDSEPDE MIYDDVENGD EGGNSSLEYG WSSSEFESYE EQSDSECK Highest antigen sequence identity to the following orthologs: Mouse - 86%, Rat - 59%.
This gene encodes a Rho guanine nucleotide exchange factor (GEF). Rho GEFs regulate the activity of small Rho GTPases by stimulating the exchange of guanine diphosphate (GDP) for guanine triphosphate (GTP) and may play a role in neural morphogenesis. Mutations in this gene are associated with slowed nerve conduction velocity (SNCV). Alternative splicing results in multiple transcript variants.
Specifications
Specifications
| Antigen | ARHGEF10 |
| Applications | Immunohistochemistry (Paraffin), Immunocytochemistry |
| Classification | Polyclonal |
| Concentration | 0.1 mg/mL |
| Conjugate | Unconjugated |
| Formulation | PBS with 40% glycerol and 0.02% sodium azide; pH 7.2 |
| Gene | ARHGEF10 |
| Gene Accession No. | O15013 |
| Gene Alias | 6430549H08Rik; Arhgef10; GEF10; Kiaa0294; mKIAA0294; RGD1565043; Rho guanine nucleotide exchange factor (GEF) 10; Rho guanine nucleotide exchange factor 10; SNCV |
| Gene Symbols | ARHGEF10 |
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