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  6. Invitrogen™ ARID1A Monoclonal Antibody (KAA140_16E7), Invitrogen™

Invitrogen™ ARID1A Monoclonal Antibody (KAA140_16E7), Invitrogen™

Product Code. 30202609
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50 μL
200 μL
Unit Size:
200µg
50µg
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30202609 50 μL 50µg
30207376 200 μL 200µg
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Product Code. 30202609 Supplier Invitrogen™ Supplier No. MA555695

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Description

Mouse Monoclonal Antibody

This gene encodes a member of the SWI/SNF family, whose members have helicase and ATPase activities and are thought to regulate transcription of certain genes by altering the chromatin structure around those genes. The encoded protein is part of the large ATP-dependent chromatin remodeling complex SNF/SWI, which is required for transcriptional activation of genes normally repressed by chromatin. It possesses at least two conserved domains that could be important for its function. First, it has a DNA-binding domain that can specifically bind an AT-rich DNA sequence known to be recognized by a SNF/SWI complex at the beta-globin locus. Second, the C-terminus of the protein can stimulate glucocorticoid receptor-dependent transcriptional activation. It is thought that the protein encoded by this gene confers specificity to the SNF/SWI complex and may recruit the complex to its targets through either protein-DNA or protein-protein interactions. Two transcript variants encoding different isoforms have been found for this gene.
TRUSTED_SUSTAINABILITY

Specifications

Antigen ARID1A
Applications Immunoprecipitation, Western Blot
Classification Monoclonal
Clone KAA140_16E7
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol, 0.5% BSA and 0.09% sodium azide
Gene ARID1A
Gene Accession No. O14497
Gene Alias 1110030E03Rik; ARID domain-containing protein 1A; ARID1A; AT rich interactive domain 1A (Swi1 like); AT rich interactive domain 1A (SWI-like); AT-rich interaction domain 1A; AT-rich interactive domain-containing protein 1A; B120; BAF250; Baf250a; BM029; brain protein 120; BRG1-associated factor 250; BRG1-associated factor 250a; C1orf4; chromatin remodeling factor p250; CSS2; ELD; h BM029; hELD; hOSA1; MRD14; Osa homolog 1; Osa1; OSA1 nuclear protein; P270; Smarcf1; SWI/SNF complex protein p270; SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily f, member 1; SWI/SNF-related, matrix-associated, actin-dependent regulator of chromatin subfamily F member 1; Swi1 like; SWI-like protein; SWI-SNF complex protein p270
Gene Symbols ARID1A
Host Species Mouse
Immunogen Recombinant human ARID1A (proprietary range information).
Purification Method Protein A
Quantity 50 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 8289
Target Species Human
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG1
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