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Invitrogen™ ARRDC3 Polyclonal Antibody
Rabbit Polyclonal Antibody
Brand: Invitrogen™ PA5109414
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Description
Immunogen sequence: MVLGKVKSLT ISFDCLNDSN VPVYSSGDTV SGRVNLEVTG EIRVKSLKIH ARGHAKVRWT ESRNAGSNTA YTQNYTEEVE YFNHKDILIG HERDDDNSEE GFHTIHSGRH EYAFSFELPQ TPLATSFEGR HGSVRYWVKA ELHRPWLLPV KLKKEFTVFE HIDINTPSLL SPQAGTKEKT LCCWFCTSGP ISLSAKIERK GYTPGESIQI FAEIENCSSR MVVPKAAIYQ TQAFYAKGKM KEVKQLVANL RGESLSSGKT ETWNGKLLKI.
Adapter protein that plays a role in regulating cell-surface expression of adrenergic receptors and probably also other G protein-coupled receptors. Plays a role in NEDD4-mediated ubiquitination and endocytosis of activated ADRB2 and subsequent ADRB2 degradation. May recruit NEDD4 to ADRB2. Alternatively, may function as adapter protein that does not play a major role in recruiting NEDD4 to ADRB2, but rather plays a role in a targeting ADRB2 to endosomes.
Specifications
| ARRDC3 | |
| Polyclonal | |
| Unconjugated | |
| ARRDC3 | |
| AI450344; alpha-arrestin 3; ARRDC3; arrestin domain containing 3; arrestin domain-containing protein 3; Kiaa1376; Liver regeneration-related protein LRRG00048; LRRGT00048; mKIAA1376; TBP-2-like inducible membrane protein; thioredoxin-binding protein-2-like inducible membrane; TLIMP | |
| Rabbit | |
| Affinity Chromatography | |
| RUO | |
| 309945 | |
| -20°C, Avoid Freeze/Thaw Cycles | |
| Liquid |
| ELISA, Western Blot | |
| 1.73 mg/mL | |
| PBS with 50% glycerol and 0.01% thimerosal; pH 7.3 | |
| Q6TXF1 | |
| ARRDC3 | |
| Recombinant fusion protein containing a sequence corresponding to amino acids 1-270 of human ARRDC3 (NP_065852.1). | |
| 100 μL | |
| Primary | |
| Rat | |
| Antibody | |
| IgG |
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