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Description
Antibody detects endogenous levels of total ARRDC3.
Adapter protein that plays a role in regulating cell-surface expression of adrenergic receptors and probably also other G protein-coupled receptors. Plays a role in NEDD4-mediated ubiquitination and endocytosis of activated ADRB2 and subsequent ADRB2 degradation. May recruit NEDD4 to ADRB2. Alternatively, may function as adapter protein that does not play a major role in recruiting NEDD4 to ADRB2, but rather plays a role in a targeting ADRB2 to endosomes.
Specifications
Specifications
| Antigen | ARRDC3 |
| Applications | Western Blot, Immunocytochemistry |
| Classification | Polyclonal |
| Concentration | 1 mg/mL |
| Conjugate | Unconjugated |
| Formulation | PBS with 50% glycerol and 0.02% sodium azide; pH 7.4 |
| Gene | ARRDC3 |
| Gene Accession No. | Q6TXF1, Q7TPQ9, Q96B67 |
| Gene Alias | AI450344; alpha-arrestin 3; ARRDC3; arrestin domain containing 3; arrestin domain-containing protein 3; Kiaa1376; Liver regeneration-related protein LRRG00048; LRRGT00048; mKIAA1376; TBP-2-like inducible membrane protein; thioredoxin-binding protein-2-like inducible membrane; TLIMP |
| Gene Symbols | ARRDC3 |
| Show More |
Product Title
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