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Invitrogen™ ARTS Polyclonal Antibody
Rabbit Polyclonal Antibody
Brand: Invitrogen™ PA582804
This item is not returnable.
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Description
Immunogen sequence: TMLVRTHMQD LKDVTRETHY ENYRAQCIQS MTRLVVKERN RNKLTRESGT DFPIPAVPPG TDPETEKLIR EKDEELRRMQ E Highest antigen sequence indentity to the following orthologs: Rat - 100%, Mouse - 100%.
Apoptosis is related to many diseases and development. Mitochondrial proteins, such as cytochrome c, Apaf-1, and AIF play important role in apoptosis. A novel mitochondrial septin-like protein was identified recently and designated ARTS for apoptosis related protein in TGF-beta signaling pathway. ARTS that is encoded by the human septin H5/PNUTL2/CDCrel2b gene is located to mitochondria and translocates to the nucleus when apoptosis occurs. ARTS is expressed in many tissues. It enhances cell death induced by TGF-beta and, to a lesser extent, by other apoptotic agents, such as TNF-a and Fas ligand.
Specifications
| ARTS | |
| Polyclonal | |
| Unconjugated | |
| SEPTIN4 | |
| 4-Sep; apoptosis-related protein in the TGF-beta signaling pathway; ARTS; Bh5; BRADEION; Bradeion beta; brain protein H5; C17orf47; CE5B3; CE5B3 beta; cell division control-related protein 2; cell division control-related protein 2b; cerebral protein 7; EG3-1RVC; EG3RVC; expression gene 3 in rat visual cortex; expression gene 3-1 in rat visual cortex; H5; hCDCREL-2; hucep-7; MART; M-Septin; OTTMUSG00000001265; peanut-like 2; peanut-like 2 homolog; peanut-like protein 2; PNUTL2; SEP4; Sept4; septin 4; septin H5; Septin4; septin-4; septin-M; Uncharacterized protein C17orf47 | |
| Rabbit | |
| Antigen affinity chromatography | |
| RUO | |
| 5414 | |
| Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. | |
| Liquid |
| Immunohistochemistry (Paraffin), Immunocytochemistry | |
| 0.10 mg/mL | |
| PBS with 40% glycerol and 0.02% sodium azide; pH 7.2 | |
| O43236 | |
| SEPTIN4 | |
| Recombinant protein corresponding to Human SEPT4. Recombinant protein control fragment (Product #RP-93188). | |
| 100 μL | |
| Primary | |
| Human | |
| Antibody | |
| IgG |
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